Some disorders related to a low BUN level in the blood are pregnancy and acromegaly. If kidneys do not work properly urea remains in the bloodstream and its concentration in the blood will be abnormally higher.Ī BUN level below the normal range may be a sign of a low-protein diet or a liver disorder (the liver is not doing a proper protein metabolism). Kidney disorders ( kidney failure, nephropathies, etc.).High protein catabolism (due to an excessive consumption of proteins, etc.).A decrease in the plasma volume due to dehydration or upper GI (gastrointestinal) bleeding.Urea level in the blood is directly related to nutrition, protein metabolism/catabolism and renal functionality.Ī high level of BUN in the blood may be due to: Urea is a marker for kidneys and liver activity. Lab Test: Blood Urea Nitrogen, BUN Level Adults: 10-20 mg/dL (3.6-7.1 mmol/L) Elderly: may be slightly higher than adult Children: 5-18 mg/dL (1.8-6.4 mmol/L). Maximum values increase with the age and are higher in elderly people. Age is an important factor to normal ranges.If your test is expressed in urea you must convert the values from urea to BUN or the information given will not be specific for your case. Warning: In this page we talk about BUN levels. It important to know if the values measured are the BUN levels used in the US and other countries or instead the values measured are the total urea used in Europe and around the world.There are some circumstances to take into account about BUN normal ranges in the blood: Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation. There may be also slight differences in the normal levels according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. For the adult female, with her generally lower muscle mass, the normal range is 0.5 to 1.1 mg/dl, or 44 to 97 μmol/L by the enzymatic method.Ĭopyright © 1990, Butterworth Publishers, a division of Reed Publishing.Each laboratory must establish its own normal ranges for BUN in the blood. For the adult male, the normal range is 0.6 to 1.2 mg/dl, or 53 to 106 μmol/L by the kinetic or enzymatic method, and 0.8 to 1.5 mg/dl, or 70 to 133 μmol/L by the older manual Jaffé reaction. The normal serum creatinine ( sCr) varies with the subject's body muscle mass and with the technique used to measure it. Pregnancy and laboratory studies: a reference table for clinicians. In contrast, the rugged rancher who eats in excess of 125 g protein each day may have a normal BUN of 20 mg/dl. Abbassi-Ghanavati M, Greer LG, Cunningham FG. Her higher glomerular filtration rate (GFR), expanded extracellular fluid volume, and anabolism in the developing fetus contribute to her relatively low BUN of 5 to 7 mg/dl. A BUN of 15 mg/dl would represent significantly impaired function for a woman in the thirtieth week of gestation. The range is wide because of normal variations due to protein intake, endogenous protein catabolism, state of hydration, hepatic urea synthesis, and renal urea excretion. The normal range of urea nitrogen in blood or serum is 5 to 20 mg/dl, or 1.8 to 7.1 mmol urea per liter. The BUN, then, is roughly one-half (28/60 or 0.446) of the blood urea. But normal ranges can vary, depending on a lab’s reference range and the age of the patient being tested. ![]() Any amount over that usually means a patient is dehydrated. ![]() The normal range for BUN levels is about 6 to 20 mg/dL or 2.1 to 7.1 mmol/L. In Europe, the whole urea molecule is assayed, whereas in the United States only the nitrogen component of urea (the blood or serum urea nitrogen, i.e., BUN or SUN) is measured. BUN level results are measured in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). However, average ranges are 0.71.2 milligrams per deciliter (mg/dL) for males and 0.51.0 for females. Both are relatively small molecules (60 and 113 daltons, respectively) that distribute throughout total body water. Average creatinine levels can vary depending on a person’s age, sex, and muscle mass. Creatinine is the product of muscle creatine catabolism. Urea is the primary metabolite derived from dietary protein and tissue protein turnover. Urea and creatinine are nitrogenous end products of metabolism.
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